Updated April 2018. Early research shows that following a reduced-calorie diet, eating two squares of dark chocolate, and drinking a sugar-free cocoa beverage daily for 18 weeks does not increase weight loss in overweight or obese individuals. Caffeine impairs glucose metabolism in type 2 diabetes. Lee, A. and Storey, D. M. Comparative gastrointestinal tolerance of sucrose, lactitol, or D-tagatose in chocolate. Psychopharmacology (Berl) 2004;176(3-4):412-419. B., and Ferri, C. Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate. View abstract. Which medications should be held before a pharmacologic or exercise stress test? Kockler DR, McCarthy MW, Lawson CL. View abstract. Spadafranca, A., Martinez, Conesa C., Sirini, S., and Testolin, G. Effect of dark chocolate on plasma epicatechin levels, DNA resistance to oxidative stress and total antioxidant activity in healthy subjects. Many dried and prepackaged coconut products are heavily sweetened, which significantly increases the sugar content. View abstract. Martin, F. P., Rezzi, S., Pere-Trepat, E., Kamlage, B., Collino, S., Leibold, E., Kastler, J., Rein, D., Fay, L. B., and Kochhar, S. Metabolic effects of dark chocolate consumption on energy, gut microbiota, and stress-related metabolism in free-living subjects. View abstract. Fluconazole (Diflucan) interacts with COCOA. View abstract. Connor WE. Memory and thinking skills (cognitive function). Beck, A. M., Damkjaer, K., and Sorbye, L. W. Physical and social functional abilities seem to be maintained by a multifaceted randomized controlled nutritional intervention among old (>65 years) Danish nursing home residents. Eur.Arch.Paediatr.Dent. But not all research agrees. It can also cause constipation and trigger migraine headaches. The role of fatty acid saturation on plasma lipids, lipoproteins, & apolipoproteins: I. View abstract. Recent advances in caffeine and theobromine toxicities: a review. Eur.J Clin Nutr 2012;66(10):1153-1159. Appl.Physiol Nutr Metab 2009;34(6):1017-1022. Am J Clin Nutr 1989;50(5):983-986. Jafarnejad S, Salek M, Clark CCT. Innes, A. J., Kennedy, G., McLaren, M., Bancroft, A. J., and Belch, J. J. 2012;23(1):15-25. J Pak Med.Assoc. View abstract. A., Tutuian, R., Orlando, R. C., and Arnold, R. Review article: the pathophysiology of gastro-oesophageal reflux disease - oesophageal manifestations. View abstract. Lee, K. W., Kundu, J. K., Kim, S. O., Chun, K. S., Lee, H. J., and Surh, Y. J. After 45 days, the coconut water group had a reduction in cholesterol and triglyceride levels that rivaled the effects of a statin drug used to lower cholesterol . Am J Clin Nutr 2004;80:22-8. Effect of consumption of cocoa-derived products on uric acid crystallization in urine of healthy volunteers. ), coconut water is one hell of a super hydrating beverage. View abstract. Yet, it’s high in calories and saturated fat, so you should eat it in moderation. Some medications for asthma include albuterol (Proventil, Ventolin, Volmax), metaproterenol (Alupent), terbutaline (Bricanyl, Brethine), and isoproterenol (Isuprel). Castillejo, G., Bullo, M., Anguera, A., Escribano, J., and Salas-Salvado, J. Pharmacotherapy 2001;21:647-51.. View abstract. J Nutr 1993;123:1611-4. View abstract. All rights reserved. Nutrients. A pharmacodynamic interaction between caffeine and phenylpropanolamine. View abstract. Taking cocoa (which contains caffeine) along with disulfiram (Antabuse) might increase the effects and side effects of caffeine including jitteriness, hyperactivity, irritability, and others. Br.J Clin Pharmacol. View abstract. Taking Mexiletine (Mexitil) along with cocoa might increase the caffeine effects and side effects of cocoa. Effect of caffeine administered intravenously on intracoronary-administered adenosine-induced coronary hemodynamics in patients with coronary artery disease. View abstract. Caffeine intake increases the rate of bone loss in elderly women and interacts with vitamin D receptor genotypes. Am J Hypertens 2005;18:785-91.. View abstract. The benefit, if any, may depend on the person's age, the duration of cocoa intake, the dose of cocoa, and the difficulty of the cognitive testing. View abstract. All rights reserved. Cone EH, Lange R, Darwin WD. If you are allergic to coconut or any of its byproducts, you will most certainly want to steer clear of consuming it in any form. View abstract. Davison, K., Coates, A. M., Buckley, J. D., and Howe, P. R. Effect of cocoa flavanols and exercise on cardiometabolic risk factors in overweight and obese subjects. Aqel RA, Zoghbi GJ, Trimm JR, et al. Buijsse B, Feskens EJ, Kok FJ, Kromhout D. Cocoa intake, blood pressure, and cardiovascular mortality: the Zutphen Elderly Study. 2008;16(3):109-115. Wakabayashi K, Kono S, Shinchi K, et al. View abstract. Effects of intentionally enhanced chocolate on mood. Food Funct. Srikanth, R. K., Shashikiran, N. D., and Subba Reddy, V. V. Chocolate mouth rinse: Effect on plaque accumulation and mutans streptococci counts when used by children. It contains a significant amount of saturated fat, which is highly controversial. (check all that apply), What factors are most important to you? Psychopharmacology (Berl). Am J Hypertens. The caffeine in cocoa can stimulate the body. View abstract. Most research shows that eating dark chocolate or cocoa products for 2-8 weeks can lower the top number in a blood pressure reading (systolic blood pressure) by 4 mmHg. View abstract. Effect of dark chocolate on arterial function in healthy individuals. Mol.Nutr Food Res 2009;53(3):322-331. Karp, J. R., Johnston, J. D., Tecklenburg, S., Mickleborough, T. D., Fly, A. D., and Stager, J. M. Chocolate milk as a post-exercise recovery aid. J Indian Soc Pedod.Prev Dent. Side Effects & Safety When taken by mouth: Eating cocoa is LIKELY SAFE for most people. 2012;25(10):1860-1867. What factors influenced or will influence your purchase? Clozapine (Clozaril) interacts with COCOA. Heiss, C., Kleinbongard, P., Dejam, A., Perre, S., Schroeter, H., Sies, H., and Kelm, M. Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysfunction in smokers. View abstract. Am J Clin Nutr 2010;92(1):218-225. Negatives sides of coconut worm Although Sago warm has nutritional value to the human body, it is also considered as a destructive pest. Farouque, H. M., Leung, M., Hope, S. A., Baldi, M., Schechter, C., Cameron, J. D., and Meredith, I. T. Acute and chronic effects of flavanol-rich cocoa on vascular function in subjects with coronary artery disease: a randomized double-blind placebo-controlled study. Nutr Clin Pract 2009;24(5):560-577. Effect of chocolate and mate tea on the lipid profile of individuals with HIV/AIDS on antiretroviral therapy: a clinical trial. 5-15-1999;149(10):943-949. Taking caffeine along with verapamil (Calan, Covera, Isoptin, Verelan) can increase the risk of caffeine side effects including jitteriness, headache, and an increased heartbeat. Med Trop.(Mars.) 2011;61(3):304-307. View abstract. View abstract. Polyphenols are an interesting area of study in nutrition. View abstract. Caffeine-induced cardiac arrhythmia: an unrecognised danger of healthfood products. Cimetidine (Tagamet) interacts with COCOA. View abstract. Aging skin. Int J Obes. [Beneficial effects of chocolate on cardiovascular health]. Maturitas 2011;69(4):312-321. View abstract. 2017;4:CD008893. Denke, M. A. Cavarretta E, Peruzzi M, Del Vescovo R, et al. 4-1-1998;147(7):620-627. Flammer, A. J., Sudano, I., Wolfrum, M., Thomas, R., Enseleit, F., Periat, D., Luscher, T. F., Ruschitzka, F. T., Noll, G., and Corti, R. Acute and chronic effects of flavonoid-rich-chocolate on endothelial function in patients with chronic heart failure (abstract). Heart 2006;92(1):119-120. 2008;26(2):67-70. Nehlig, A. View abstract. Yochum, L., Kushi, L. H., Meyer, K., and Folsom, A. R. Dietary flavonoid intake and risk of cardiovascular disease in postmenopausal women. Caffeine withdrawal increases lithium blood levels. View abstract. J Agric.Food Chem. Avisar R, Avisar E, Weinberger D. Effect of coffee consumption on intraocular pressure. Am J Clin Nutr 2015;101(3):538-48. Are lifestyle measures effective in patients with gastroesophageal reflux disease? 2017;9(7). Spencer, J. P., Schroeter, H., Rechner, A. R., and Rice-Evans, C. Bioavailability of flavan-3-ols and procyanidins: gastrointestinal tract influences and their relevance to bioactive forms in vivo. 2017;183:18-23. In fact, 1 tbsp of coconut … Larsson, S. C., Virtamo, J., and Wolk, A. Thus, unsweetened or raw products are healthiest. A major nutritional disadvantage of coconut flesh is its high saturated fat content. Cardiol.Rev. Camfield, D. A., Scholey, A., Pipingas, A., Silberstein, R., Kras, M., Nolidin, K., Wesnes, K., Pase, M., and Stough, C. Steady state visually evoked potential (SSVEP) topography changes associated with cocoa flavanol consumption. Hertog MG, Feskens EJ, Hollman PC, et al. Nutr Res 2006;26:509-516. View abstract. Lancet 6-20-1981;1(8234):1340-1342. Mol.Nutr Food Res 2008;52(10):1215-1227. View abstract. Caffeine ingestion increases the insulin response to an oral-glucose-tolerance test in obese men before and after weight loss. Fluconazole (Diflucan) might decrease how quickly the body gets rid of caffeine. 2010;24(9):568-576. Large piles of ripe sorted coconuts. You’ll need to pierce its soft spots — or eyes — with a hammer and nail, then drain the milk, after which you can break the husk. Our advice: Make it a priority to ramp up your coconut water intake in 2020. Taking these antibiotics along with cocoa can increase the risk of side effects including jitteriness, headache, increased heart rate, and other side effects. Lithium tremor and caffeine intake: two cases of drinking less and shaking more. Cocoa contains caffeine. Virgin coconut oil is the purest form of the oil. Caffeine can increase how much Ergotamine the body absorbs. Peirce A. View abstract. Mexiletine (Mexitil) can decrease how quickly the body breaks down caffeine. View abstract. It might cause fullness or stomach upset in some people. Ottaviani, J. I., Momma, T. Y., Heiss, C., Kwik-Uribe, C., Schroeter, H., and Keen, C. L. The stereochemical configuration of flavanols influences the level and metabolism of flavanols in humans and their biological activity in vivo. Acute cocoa supplementation increases postprandial HDL cholesterol and insulin in obese adults with type 2 diabetes after consumption of a high-fat breakfast. View abstract. Alspach, G. The truth is often bittersweet...: chocolate does a heart good. A Healthy Oil for Cooking. Umemura, T., Ueda, K., Nishioka, K., Hidaka, T., Takemoto, H., Nakamura, S., Jitsuiki, D., Soga, J., Goto, C., Chayama, K., Yoshizumi, M., and Higashi, Y. 11-15-2012;527(2):90-94. Most of these fats are medium-chain triglycerides (MCTs), which are absorbed intact in your small intestine and used by your body to produce energy (5). The Side Effects and Health Risks of Coconut. Biol Psychiatry 1995;37:348-50. Caffeine can increase how much ergotamine (Ergomar) the body absorbs. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Am J Clin Nutr 2005;81:611-14. View abstract. View abstract. It can benefit health in several ways, such as by stimulating weight loss and lowering cholesterol. Loffredo, L., Carnevale, R., Perri, L., Catasca, E., Augelletti, T., Cangemi, R., Albanese, F., Piccheri, C., Nocella, C., Pignatelli, P., and Violi, F. NOX2-mediated arterial dysfunction in smokers: acute effect of dark chocolate. The starting material for cocoa and chocolate is the seed of Theobroma cacao which are embedded in the pulp of the tree pods (Money, 2016). Efficacy of calcium supplements on bone mass in postmenopausal women. JAMA 2003;290:1029-30.. View abstract. 2018;10(10). View abstract. View abstract. The fruit looks like little melons with the pulp inside containing 20 to 30 cocoa seeds . One 4-week study gave 91 people 1.6 ounces (50 ml) of either extra virgin coconut oil, extra virgin olive oil, or unsalted butter daily. What’s more, coconut oil may reduce the growth of harmful yeasts, such as Candida albicans, which can cause serious infections (19). If you take products that contain caffeine and you take lithium, stop taking caffeine products slowly. View abstract. Diabetes medications are used to lower blood sugar. Galleano, M., Oteiza, P. I., and Fraga, C. G. Cocoa, chocolate, and cardiovascular disease. View abstract. Some antibiotics that decrease how quickly the body breaks down caffeine include ciprofloxacin (Cipro), enoxacin (Penetrex), norfloxacin (Chibroxin, Noroxin), sparfloxacin (Zagam), trovafloxacin (Trovan), and grepafloxacin (Raxar). View abstract. Moco, S., Martin, F. P., and Rezzi, S. Metabolomics view on gut microbiome modulation by polyphenol-rich foods. Abnormal levels of blood fats in people with HIV/AIDS. View abstract. Scholey, A. Sklar S, et al. View abstract. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. Nutr Rev. Mellor, D. D., Sathyapalan, T., Kilpatrick, E. S., Beckett, S., and Atkin, S. L. High-cocoa polyphenol-rich chocolate improves HDL cholesterol in Type 2 diabetes patients. 2012;59:127-134. Curr Atheroscler.Rep. View abstract. Int J Hypertens. Todd, S., Corsnitz, D., Ray, S., and Nassar, J. Outpatient laparoscopic Nissen fundoplication. Di Renzo, G. C., Brillo, E., Romanelli, M., Porcaro, G., Capanna, F., Kanninen, T. T., Gerli, S., and Clerici, G. Potential effects of chocolate on human pregnancy: a randomized controlled trial. Consuming cocoa with these medications used for depression might cause too much stimulation. Larsson SC, Drca N, Jensen-Urstad M, Wolk A. Am.J Clin.Nutr. J Sports Med Phys Fitness 2000;40:71-9. This translates to having lesser "side effects" from consuming MCT oil or virgin coconut oil. The effect of flavanol-rich cocoa on cerebral perfusion in healthy older adults during conscious resting state: a placebo controlled, crossover, acute trial. View abstract. View abstract. Ried K, Fakler P, Stocks NP. View abstract. Differential effect of cocoa drinks with low and high theobromine dose on peripheral and central blood pressure: A double blind placebo controlled randomised cross-over trial (abstract). View abstract. Cocoa contains caffeine. Corti, R., Flammer, A. J., Hollenberg, N. K., and Luscher, T. F. Cocoa and cardiovascular health. 2007;9(8):647-648. View abstract. Taking cocoa powder along with Ergotamine may increase the effects and side effects of the medication. J Am Coll.Cardiol. Ried, K., Sullivan, T. R., Fakler, P., Frank, O. R., and Stocks, N. P. Effect of cocoa on blood pressure. This is because, it bore holes in a coconut tree, date palm, and palm tree killing them completely. Am J Clin Nutr 1994;60(6 Suppl):1014S-1016S. Eur.J Clin.Nutr. Di, Castelnuovo A., di, Giuseppe R., Iacoviello, L., and de, Gaetano G. Consumption of cocoa, tea and coffee and risk of cardiovascular disease. Crit Care Nurse 2007;27(1):11-15. Coco plum scientifically known as Chrysobalanus icaco is a slow growing tree belonging to the chrysobalanaceae family. View abstract. J Anal Toxicol 1998;22:460-73. This is a detailed article about coconut oil and its health benefits. View abstract. Am J Clin Nutr 2013;97(6):1201-9. The body breaks down caffeine to get rid of it. Cocoa Extract Side Effects and Dosage Am J Emerg.Med. A., Novotny, J. Stanek EJ, Melko GP, Charland SL. Nutr J 2010;9:55. 2011;12(5):245-249. Too Much Potassium Spells Problems for Your Heart. Heinrich, U., Neukam, K., Tronnier, H., Sies, H., and Stahl, W. Long-term ingestion of high flavanol cocoa provides photoprotection against UV-induced erythema and improves skin condition in women. Kris-Etherton PM, Derr J, Mitchell DC, et al. Lancet 1993;342:1007-1011. www.medscape.com/reuters/prof/2000/02/02.21/dd02210b.html (Accessed 21 February 2000). Coconut meat is particularly high in calories, saturated fat, and fiber. The debate on whether or not coconut oil had unhealthy side effects is mixed, because coconut is a plant. 2002;62(5):511-516. Early research shows that eating 200 mg of dark chocolate does not improve movement in people with Parkinson disease. Bruinsma K, Taren DL. 1992;31(1):40-48. J Psychopharmacol. 2006;64(3):109-118. View abstract. Watson JM, Sherwin RS, Deary IJ, et al. Harder S, Fuhr U, Staib AH, Wolff T. Ciprofloxacin-caffeine: a drug interaction established using in vivo and in vitro investigations. Decline in memory and thinking skills in older people that is more than what is normal for their age. Sorond, F. A., Lipsitz, L. A., Hollenberg, N. K., and Fisher, N. D. Cerebral blood flow response to flavanol-rich cocoa in healthy elderly humans. Here are 8 science-based benefits. This article tells you everything you need to know about coconut meat, including its nutrients, benefits, and downsides. 2012;22(2):e3-e4. Caffeine can stimulate the body. Friedman G. Diet and the irritable bowel syndrome. Verapamil (Calan, Covera, Isoptin, Verelan) interacts with COCOA. View abstract. Matsumoto, M., Tsuji, M., Okuda, J., Sasaki, H., Nakano, K., Osawa, K., Shimura, S., and Ooshima, T. Inhibitory effects of cacao bean husk extract on plaque formation in vitro and in vivo. View abstract. Some research shows that eating cocoa lowers the chance of heart disease and death. But cocoa doesn't seem to blood sugar levels, especially when used in small amounts or in single doses. Comparison of chocolate to cacao-free white chocolate in Parkinson's disease: a single-dose, investigator-blinded, placebo-controlled, crossover trial. Rich in fiber and MCTs, it may offer a number of benefits, including improved heart health, weight loss, and digestion. High cholesterol. View abstract. Fortschr Med 1995;113:291-2. View abstract. View abstract. 10. Jefferson JW. A meta-analysis. The chemical composition of cocoa pods skin contains crude protein between 6.80-13.78%; SDN 55.30-73.90% and SDA 38.31-58.98% . Eur.J Nutr 2007;46(1):53-56. 2006;47 Suppl 2:S197-S205. 12-1-2006;98(11):1538-1541. View abstract. Zomer, E., Owen, A., Magliano, D. J., Liew, D., and Reid, C. M. The effectiveness and cost effectiveness of dark chocolate consumption as prevention therapy in people at high risk of cardiovascular disease: best case scenario analysis using a Markov model. Benowitz NL, Osterloh J, Goldschlager N, et al. Sola, R., Valls, R. M., Godas, G., Perez-Busquets, G., Ribalta, J., Girona, J., Heras, M., Cabre, A., Castro, A., Domenech, G., Torres, F., Masana, L., Angles, N., Reguant, J., Ramirez, B., and Barriach, J. M. Cocoa, hazelnuts, sterols and soluble fiber cream reduces lipids and inflammation biomarkers in hypertensive patients: a randomized controlled trial. shredding it to add to fruit salad, mixed greens, blending it into smoothies, dips, and sauces. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter. View abstract. View abstract. View abstract. View abstract. Taking cocoa along with fluconazole (Diflucan) might increase the risk of caffeine side effects such as nervousness, anxiety, and insomnia. Curr Drug Deliv. Massey LK. J Hypertens 2010;28:e15. Pakistan J Nutr 2008;7(6):773-781. Well, consumption of coconut oil may also cause diarrhoea and other symptoms related to the intestine. Feldens, C. A., Vitolo, M. R., and Drachler, Mde L. A randomized trial of the effectiveness of home visits in preventing early childhood caries. Milk decreases urinary excretion but not plasma pharmacokinetics of cocoa flavan-3-ol metabolites in humans. 5-16-2007;55(10):3926-3935. This could cause serious side effects including fast heartbeat, high blood pressure, nervousness, and others. View abstract. View abstract. Cocoa to improve walking performance in older people with peripheral artery disease: the COCOA-PAD pilot randomized clinical trial. J Nutr 2006;136(5):1150-1155. View abstract. Taking cocoa along with clozapine (Clozaril) can increase the effects and side effects of clozapine (Clozaril). pii: E688. 2003;14(5):325-327. McBrier, N. M., Vairo, G. L., Bagshaw, D., Lekan, J. M., Bordi, P. L., and Kris-Etherton, P. M. Cocoa-based protein and carbohydrate drink decreases perceived soreness after exhaustive aerobic exercise: a pragmatic preliminary analysis. J Proteome.Res 2009;8(12):5568-5579. J Am Diet.Assoc. Engler, M. B., Engler, M. M., Chen, C. Y., Malloy, M. J., Browne, A., Chiu, E. Y., Kwak, H. K., Milbury, P., Paul, S. M., Blumberg, J., and Mietus-Snyder, M. L. Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults. Daily consumption of chocolate rich in flavonoids decreases cellular genotoxicity and improves biochemical parameters of lipid and glucose metabolism. Antibiotics (Quinolone antibiotics) interacts with COCOA. Nahas, R. Complementary and alternative medicine approaches to blood pressure reduction: An evidence-based review. View abstract. Davison, K., Berry, N. M., Misan, G., Coates, A. M., Buckley, J. D., and Howe, P. R. Dose-related effects of flavanol-rich cocoa on blood pressure. View abstract. J Cardiovasc.Pharmacol. Arch Intern Med 1995;155:2005-7. Wahllander A, Paumgartner G. Effect of ketoconazole and terbinafine on the pharmacokinetics of caffeine in healthy volunteers. 2004;20 Suppl 9:14-25. View abstract. As with berries and leafy greens, the darker the color of the chocolate, the more antioxidant properties it contains and the better it is for you. The following doses have been studied in scientific research: BY MOUTH: Did you or will you purchase this product in-store or online? Mellor, D. D., Madden, L. A., Smith, K. A., Kilpatrick, E. S., and Atkin, S. L. High-polyphenol chocolate reduces endothelial dysfunction and oxidative stress during acute transient hyperglycaemia in Type 2 diabetes: a pilot randomized controlled trial. Cocoa can cause allergic skin reactions, constipation, and might trigger migraine headaches. The caffeine in cocoa seems to decrease how quickly the body breaks down clozapine (Clozaril). Zheng XM, Williams RC. Decroix L, De Pauw K, Van Cutsem J, Pattyn N, Heyman E, Meeusen R. Acute cocoa flavanols intake improves cerebral hemodynamics while maintaining brain activity and cognitive performance in moderate hypoxia. d'El-Rei, J., Cunha, A. R., Burla, A., Burla, M., Oigman, W., Neves, M. F., Virdis, A., and Medeiros, F. Characterisation of hypertensive patients with improved endothelial function after dark chocolate consumption. Cocoa contains caffeine. B. Caffeine intake and low birth weight: a population-based case-control study. Free Radic.Biol Med. Coconut meat is the white flesh of coconuts and is edible fresh or dried. A pharmacological review. View abstract. The only major side effect that has been found when it comes to consuming it as a health supplement is the risk of food allergies. Cocoa and cardiovascular health]. View abstract. View abstract. Look for unsweetened or raw products to minimize your sugar intake. Desch, S., Kobler, D., Schmidt, J., Sonnabend, M., Adams, V., Sareban, M., Eitel, I., Bluher, M., Schuler, G., and Thiele, H. Low vs. higher-dose dark chocolate and blood pressure in cardiovascular high-risk patients. Gomez-Juaristi, M., Gonzalez-Torres, L., Bravo, L., Vaquero, M. P., Bastida, S., and Sanchez-Muniz, F. J. Br.J Nutr 2010;103(7):1008-1014. Thyroid hormone use and bone mineral density in elderly men. View abstract. Am J Clin Nutr 2007;85(3):709-717. 5th ed. Tokede, O. Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. Fotherby, M. D., Ghandi, C., Haigh, R. A., Macdonald, T. A., and Potter, J. F. Sustained caffeine use has no pressor effect in the elderly. Effects on blood pressure of drinking green and black tea. View abstract. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Martin, F. P., Antille, N., Rezzi, S., and Kochhar, S. Everyday eating experiences of chocolate and non-chocolate snacks impact postprandial anxiety, energy and emotional states. View abstract. Milliron, T., Kelsberg, G., and St, Anna L. Clinical inquiries. 2018;23(9). View abstract. Physiol Behav. Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.